Osteomyelitis research paper

Assignment:

Osteomyelitis research paper: The assignment consists in finding the meaning of:
Osteomyelitis, and the implications of this problem. Make a short comment about the prevention and treatment.
How to submit your Osteomyelitis research paper assignment:

Go and click on LESSONS on the left menu of the Blackboard course.
Look for the specific Chapter.
Open your assignment clicking under the Research Assignment.
Read the instructions.
Build your assignment as a WORD document independent from the Blackboard system.
Copy and paste your WORD paragraph into the assignment submission section by clicking on:
TEXT SUBMISSION – Write submission. (Not inside the window for Comments)
After that click, a window for the submission will open and now you can paste your WORD
document into that window.
Scroll down all the way and find the place for SUBMIT. Click on that and it is ready submitted.

NOTE: Please try not to attach a file instead, because it will make it more complicated to open and grade your assignment.

Looking for nursing papers writing help? Top Nursing Papers Writing Service Online is here. A team of professional nursing essay writers ready to help. Relieve academic stress! With you all through your education course. There is no nursing subject we cannot handle.

Top nursing paper writers on hand to assist you with assignment : Osteomyelitis research paper

Bone infection is called osteomyelitis. It is an acute or chronic inflammatory process involving the bone and its structures secondary to infection with pyogenic organisms, including bacteria, fungi, and mycobacteria. Interestingly, archeological finds showed animal

fossils with evidence of bone infection, making this a relatively old disease.[1] Various terms were used to describe infected bone over the years until Nelaton came up with the term osteomyelitis in 1844.[1] Before the introduction of penicillin in the 1940s, management of osteomyelitis was mainly surgically consisting of extensive debridement, saucerization, and wound packing following which the affected area is left to heal by secondary intention[1] resulting in high mortality from sepsis. Since the availability of antibiotics, mortality rates from osteomyelitis, including staphylococcal osteomyelitis, has improved significantly.

Go to:
Etiology
Healthy intact bone is resistant to infection. The bone becomes susceptible to disease with the introduction of a large inoculum of bacteria, from trauma, ischemia, or the presence of foreign bodies because bone sites to which microorganisms can bind are exposed.[2] Certain bacteria such as Staphylococcus aureus adhere to the bone by expressing receptors, called adhesins, for some components of the bone matrix, including laminin, collagen, fibronectin, and bone sialoglycoprotein. S. aureus expresses a collagen-binding adhesin, which permits its attachment to bone cartilage while the fibronectin-binding adhesin’s role in attachment of bacteria to surgically implanted devices in bone was recently discovered.[2] Also interesting to note is that S. aureus can survive intracellularly after being internalized by cultured osteoblasts. Some bacteria create a protective biofilm coating around themselves and underlying surfaces. This characteristic of some bacteria to adhere to the bone and surgically implanted devices following which they express phenotypic resistance to antibiotic therapy and their ability to survive intracellularly may explain the persistence of bone infections and high failure rates of shorter courses of antimicrobial treatment.[2]

Go to:
Epidemiology
The overall incidence of osteomyelitis in the United States is mostly unknown, but reports show it to be as high as 1 in 675 US hospital admissions each year or about 50,000 cases annually.[3] Other studies show an overall incidence of osteomyelitis of 21.8 cases per 100,000 person-years.[4] The incidence was higher in men for unknown reasons but increases with age, mainly due to an increase in the prevalence of comorbid factors such as diabetes mellitus and peripheral vascular disease.[4] Also, an increase in the availability of sensitive imaging tests, such as magnetic resonance imaging (MRI) and bone scintigraphy has improved diagnostic accuracy and the ability to characterize the infection

Osteomyelitis research paper