NURS350 Assignment: Research Questions Using PICOT

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PICOT is an acronym used to help develop clinical research questions and guide you in your search for evidence:

P = Patient population

I = Intervention or issue of interest

C = Comparison of interventions or comparison of interests

O = Outcome

T = Time frame

For example, you may wish to research if the timing of IV tubing changes affects the development of CLABSI, using this PICOT model:

In _____(P), what is the effect of _____(I) on ____(O) compared with _____(C) within ______ (T)?

In patients on the acute care medical surgical floor (P), what is the effect of changing continuous IV tubings every 96 hours (I) on the incidence of CLABSI (O) versus every changing continuous IV tubings every 48 hours (C) during a 6-month tracking period (T)?

Assignment Directions

Begin by selecting a topic in nursing or medicine that is of interest to you. Next, use PICOT to format possible research questions about that topic. Provide three possible PICOT research questions related to the chosen topic (each question will have a different direction on the same topic).

NURS350 Assignment: Clinical Issue and Research Questions Using PICOT — NURS350 Assignment: Research Questions Using PICOT

Include the following:

Provide a brief description of the topic and background information.

Explain the significance of the topic to nursing practice.

Provide three clearly stated PICOT questions.

Your paper should:

Include a Title page and a Reference page.

Be 2–3 pages (not including the title page and reference list).

Use current APA Style to format your paper and to cite your sources.

Review the rubric for further information on how your assignment will be graded.

background. We report a meta-analysis of 4 identical time-series cohort studies of the impact of switching from use of open infusion

containers (glass bottle, burette, or semirigid plastic bottle) to closed infusion containers (fully collapsible plastic containers) on central

line–associated bloodstream infection (CLABSI) rates and all-cause intensive care unit (ICU) mortality in 15 adult ICUs in Argentina,

Brazil, Italy, and Mexico.

methods. All ICUs used open infusion containers for 6–12 months, followed by switching to closed containers. Patient characteristics,

adherence to infection control practices, CLABSI rates, and ICU mortality during the 2 periods were compared by x

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test for each country,

and the results were combined using meta-analysis.

results. Similar numbers of patients participated in 2 periods (2,237 and 2,136). Patients in each period had comparable Average

Severity of Illness Scores, risk factors for CLABSI, hand hygiene adherence, central line care, and mean duration of central line placement.

CLABSI incidence dropped markedly in all 4 countries after switching from an open to a closed infusion container (pooled results, from

10.1 to 3.3 CLABSIs per 1,000 central line–days; relative risk [RR], 0.33 [95% conﬁdence interval {CI}, 0.24–0.46]; ). All-causeP!.001

ICU mortality also decreased signiﬁcantly, from 22.0 to 16.9 deaths per 100 patients (RR, 0.77 [95% CI, 0.68–0.87]; ).P!.001

conclusions. Switching from an open to a closed infusion container resulted in a striking reduction in the overall CLABSI incidence

and all-cause ICU mortality. Data suggest that open infusion containers are associated with a greatly increased risk of infusion-related

bloodstream infection and increased ICU mortality that have been unrecognized. Furthermore, data suggest CLABSIs are associated with

signiﬁcant attributable mortality

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NURS350 Assignment: Research Questions Using PICOT