NR 507 Week 4 Midterm Exam Practice Questions and Answers
Epigenetics
Defects in the encoding of histone-modifying proteins
Epigenetics and its role on human development
Totipotent cells and its ability to differentiate into any type of cell
Prader-Willi syndrome and Angelman syndrome?
Cellular Proliferation
5-Azacytidine and the treatment of canceR
the role of inactive MLH1 in the development of some forms of inherited colon cancer
Effects of ethanol on neural stem cells ability to differentiate into functional neurons-
Inflammation as an etiology for cancer-note conditions in which this may occur
Cancer
In terms of epigenetic modifications, the role of environmental stressors associated with development of cancer
Defects in Mechanism of Defense
Hemolytic defects in the newborn
Understand the meaning of infectivity
Most effective treatment for HIV
Defected cells of HIV
Signs of T-Lymphocyte deficiency-
Pulmonary Alterations
Pulmonary function tests
Relationship of lung compliance and residual volumE
Shifts in the oxyhemoglobin dissociation
CO2 transport in the blood
Characteristics of alveoli
Arterial perfusion pressure and alveolar gas pressure in the lung base
How do determine the partial pressure of oxygen given the percentage of oxygen in the air and the barometric pressure
Results of increased work of breathing
Know terms:
Vital capacity (VC),
Vital Capacity
Can’t take in as much air because elasticity is reduced
Functional capacity
Residual volume,-
Functional residual capacity (FRC)
Renal Alterations
Types of nephrons and their functions
Overall renal physiology
Substances that are actively secreted by the renal tubules
Activation of the renin-angiotensin system
Glomerular filtration rate
Mesangial cells
Renal system anatomy
Why plasma proteins should … absent from the urine
Effects of urinary tract obstruction- hydronephrosis and a decreased glomerular filtration rate
Effect of urinary retention
Most common type of renal stone
Epispadias
PIC: A=normal, B=clitoris altered, C and D=varying degree of urethral defect
Glomerulonephritis
Nephrotic syndrome
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