Disorders of Glycogen and Fatty Acid Metabolism Presentation

INSTRUCTIONS
You will choose a metabolic disorder from the Module: Week’s readings and submit a detailed
PowerPoint on the chosen disorder. You should research the
disease extensively using at least 5 peer-reviewed journal articles or textbooks. Be sure to use the
suggested outline for your presentation. Refer to the grading rubric for a breakdown of the points
allocation. The presentation has a 10 minute time limit. There should be at least 10 citations all
in AMA format.

VIDEO PRESENTATION: DISORDERS OF GLYCOGEN AND FATTY ACID METABOLISM
 Using the suggested outline below, give a detailed research presentation on any disorder of
glycogen or fatty acid metabolism of your choice. You should employ scientific
sources/literature including review articles in your research and be sure to use the AMA
format. It should be detailed, comprehensive, well-organized and should have the appropriate
language for scientific communication.

Outline:
– Introduction
– Epidemiology
– Etiology
– Types/ Classification
– Signs/ Symptoms
– Normal and Abnormal Biochemistry
– Pathologic Features/Genetic Basis of Disease
– Laboratory Features
– Differential Diagnosis
– Management/ Treatment
– Complications
– Prognosis
– Current/ Future Research (Including Clinical Trials)

Causes
Metabolic syndrome is closely linked to overweight or obesity and inactivity.

It’s also linked to a condition called insulin resistance. Normally, your digestive system breaks down the foods you eat into sugar. Insulin is a hormone made by your pancreas that helps sugar enter your cells to be used as fuel.

In people with insulin resistance, cells don’t respond normally to insulin and glucose can’t enter the cells as easily. As a result, your blood sugar levels rise even as your body churns out more and more insulin to try to lower your blood sugar.

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Risk factors
The following factors increase your chances of having metabolic syndrome:

Age. Your risk of metabolic syndrome increases with age.
Ethnicity. In the United States, Hispanics — especially Hispanic women — appear to be at the greatest risk of developing metabolic

syndrome. The reasons for this are not entirely clear.
Obesity. Carrying too much weight, especially in your abdomen, increases your risk of metabolic syndrome.
Diabetes. You’re more likely to have metabolic syndrome if you had diabetes during pregnancy (gestational diabetes) or if you have a family history of type 2 diabetes.
Other diseases. Your risk of metabolic syndrome is higher if you’ve ever had nonalcoholic fatty liver disease, polycystic ovary syndrome or sleep apnea.
Complications
Having metabolic syndrome can increase your risk of developing:

Type 2 diabetes. If you don’t make lifestyle changes to control your excess weight, you may develop insulin resistance, which can cause your blood sugar levels to rise. Eventually, insulin resistance can lead to type 2 diabetes.
Heart and blood vessel disease. High cholesterol and high blood pressure can contribute to the buildup of plaques in your arteries. These plaques can narrow and harden your arteries, which can lead to a heart attack or stroke.