Chronic Stress and Behavioral Response
Chronic Stress and Behavioral Response
Chronic Stress and Behavioral Response
Overview of the Assignment
Cortisol is a key hormone released during the stress response. In this module assignment, we will look more closely at this hormone to investigate:
Cortisol’s molecular composition the signaling pathway that causes cortisol production and release the cellular-, organ-, and organ system-level response that results from this cell signal Case Assignment
Check out the following articles:
Cortisol and the Hypothalamic-Pituitary-Adrenal Axis in Stress Physiology M. Randall. Dartmouth Undergraduate Journal of Science, 2011.
and
The Interaction of Traumatic Stress, PTSD, and Cortisol. Naval Center for Combat and Operational Stress Control, Delaney, E.
After reading these articles, create a 10-15 slide presentation in the format shown below.
Slides 1 and 2 depict the hormonal signal cascade described in Randall’s (2011) article’s section titled “Neurochemistry of Stress.” To represent the regions that release specific hormones in the hormone cascade that results in cortisol release, use simple ovals or circles. Textboxes can be used to label the hormones, regions, and organs involved (both options are available in the PowerPoint program’s “Insert” tab).
Label and diagram the kidney and adrenal gland on slides 3 and 4. Include the following items:
Cortex and medulla of the adrenal gland; regions associated with hormone production and release; hormones released in each region
Kidney cortex and medulla; water absorption and filtering region; urine collection region
Diagram and label the HPA axis on slide 5. Include the hormones produced by each component as well as their impact on the target organ (s).
Slide 6: Include the location of the hippocampus and the negative feedback loop that occurs when the hippocampus detects high cortisol levels in your diagram from Slide 5. Include a brief description of the effects of elevated cortisol exposure on the hippocampus in the notes section.
Slide 7: Using bulleted points, list factors that exacerbate the stress response via HPA axis activation.
Slides 8-10: Conduct additional PTSD research. Draw a diagram of the brain regions thought to be involved in PTSD symptoms. Explain the connection between PTSD and depression, and include relevant brain regions in your labeled regions.
Slides 11-13: Summarize the various findings in the studies described in the article “The Relationship between Traumatic Stress, PTSD, and Cortisol” in bulleted points. Include the correlations discovered between cortisol levels and PTSD patients. Some explanations from the article for the variability in cortisol levels in these individuals are included in the notes. Explain the limitations of the studies mentioned at the end of the article by the author.
Slides 14 and 15: citations and additional notes as needed
Expectations for the Assignment
You will create a PowerPoint presentation with approximately 15 slides that addresses the requirements outlined above for this Case Assignment. Insert the text that answers the questions above into the Notes section of your slide presentation. Cite all of your answers in your Notes sections, for example (Murray 2014). Your slides should include labeled images that illustrate the text in your Notes sections. To find diagrams of the required organs and systems, conduct a Google search that includes the term “image” (for example, “adrenal gland image”). Give the URL or reference for each labeled image. Make sure your final slide is a references slide with the complete references cited on your slides. There are numerous resources available to you. Include these in your bibliography. This assignment should not necessitate a lot of independent research.
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