Assignment: NUR 550 Translational Research

Assignment: NUR 550 Translational Research

Assignment: NUR 550 Translational Research

Translational Research Graphic Organizer

Use the “Translational Research Graphic Organizer Template” to compare three types of translational research with traditional (qualitative or quantitative) research. Make sure to include methodology, goals, and data collection in your organizer.

You are required to cite three to five sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

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What is Translational in health?

THE TRANSLATION OF THE ACHIEVEMENTS FROM BASIC SCIENCE into everyday clinical practice remains an important issue in contemporary health, and is addressed through the new subject of translational research, which aims to bridge the gap between basic research and its application in health. At first, it connected bench (basic) to bed research (clinical applications), which is also known as benchside-to-bedside research2. The definition of translational research has evolved over time, ceasing to be a field linked to clinical research, with perspectives that were mainly focused on the development of new health technologies.

Assignment: NUR 550 Translational Research

There is an emerging consensus on four perspectives that comprise different stages of translational research in their broad scope based on their different purposes. The first phase involves processes that bring the ideas and the discoveries of basic research at an early stage to their application in human beings. The second phase involves the establishment of efficacy in humans and clinical guidelines for the incorporation of the clinical knowledge into practice in health systems and services. The third phase focuses mainly on implementation research and the dissemination of the application of knowledge. The fourth phase focuses on results on patients and population effectiveness, as well as equity-related issues, in order to verify whether the expected effects of technologies introduced into the health system were different across population groups.

Currently, the European Society for Translational Medicine defines a broader scope for translational research as: an interdisciplinary branch of biomedical research supported by three pillars: bench, bed, and community research, whose goal is to combine subjects, resources, knowledge, and techniques, in order to promote advances in prevention, diagnosis, and therapies, aiming to significantly improve the global health system3.

The extension of the concept to health systems seems so obvious that one wonders why translational research has only recently caught the attention of health policy managers4. The field of translational research encompasses laboratory studies, clinical demands, public health and health management, policies, and economics. It is crucial in the evolution of contemporary biomedical science, and its interventions follow political-economic, ethical-social, and educational-scientific approaches. Translational research may progress by reorganizing academic teams translationally. New translation-oriented academic positions are urgently needed1. One of the reasons for the distance between basic research and its applications may lie in the increasing compartmentalization of science. Basic research, which seeks to discover the underlying principles of the natural world, is fundamentally different from applied research, which seeks to find ways to influence or control the world. Basic and applied research scientists not only differ in their training and in the tools, they bring to solve research problems, but also in the way they plan the health research process.

Assignment: NUR 550 Translational Research

Aspects related to policy implementation and the development of other technology modalities, other than drugs and diagnostic testing, have gradually attracted the attention and interest of the academic community and decision-makers around the world. Increasingly, translational research also means translating knowledge into political and organizational praxis.

In order to move forward in this direction, translational research has broadened its scope and built connections to align itself with the translation of knowledge. It is defined as a systematic and transparent process of synthesis, dissemination, exchange, and ethical application of knowledge to improve results and strengthen public policies and health systems, as well as population health, encompassing all the phases in between production and effective application of scientific knowledge, in its various modalities and epistemological and methodological perspectives, in order to support more beneficial results for society.

In this class we will be exploring translational research and Evidence Based Practice as well as forming a PICOT question. This will be a very busy week as translational research may be a new topic for you and you will need to decide on a population and intervention to begin your PICOT question. Our goals for this week are:

Identify the different levels of translational research.
Differentiate translational research from evidence-based practice.
Discuss the application of translational research to population health management.
Evaluate sources of translational research.
Select a valid nursing practice problem for an evidence-based practice project proposal.

Please proceed to the Class Wall and tell us a little about yourself. When you complete your introduction be sure to read the policies, syllabus and weekly expectations.

You will be expected to submit answers to two DQs and to respond to at least three peers. Two posts will be your DQs and you need a minimum of 3 responses in addition to your 2 DQs. Each DQ must be at least 150 words or 12 sentences and must have two references and citations. Quotes are not allowed. Responses must be at least 75 words or 5 sentences and have one reference and a citation.

Be sure to review all the Study Materials as well as find the website for your state or county health department as your PICOT question must be based on a mortality/morbidity indicator related to a clinical problem pertaining to a population. When forming your question DO NOT use any content related to nurse staffing, staffing ratios, staffing levels (shortages) or any major system-level changes.  A template is provided in your materials for the beginning of your PICOT question.  You must use this template.

Please be sure to use the link to the GCU library provided and then click on Translational Research on the left as you will need this site to search for the literature you will need and to answer your DQs.

Refer to the calendar for the due date of the assignments. Be sure to submit your papers to LopesWrite to evaluate for plagiarism. However, please note that your first paper due this week does not need to be submitted to LopesWrite.

Please use the Questions to Instructor forum for your questions or your Private Forum for private communication. You may also reach me at between the hours of 8AM-8PM EST. All questions are welcome.

Course Code Class Code Assignment Title Total Points
NUR-550 NUR-550-O500 Translational Research Graphic Organizer 100.0

Criteria Percentage Unsatisfactory (0.00%) Less than Satisfactory (80.00%) Satisfactory (88.00%) Good (92.00%) Excellent (100.00%)
Translational Research Graphic Organizer 100.0%
Comparison of Research in Relation to Methodology 25.0% A comparison of research in relation to methodology is not included. A comparison of research in relation to methodology is present, but it lacks detail or is incomplete. A comparison of research in relation to methodology is present. A comparison of research in relation to methodology is clearly provided and well developed. A comprehensive comparison of research in relation to methodology is thoroughly developed with supporting details.

Comparison of Research in Relation to Goals 25.0% A comparison of research in relation to goals is not included. A comparison of research in relation to goals is present, but it lacks detail or is incomplete. A comparison of research in relation to goals is present. A comparison of research in relation to goals is clearly provided and well developed. A comprehensive comparison of research in relation to goals is thoroughly developed with supporting details.

Comparison of Research in Relation to Data Collection 25.0% A comparison of research in relation to data collection is not included. A comparison of research in relation to data collection is present, but it lacks detail or is incomplete. A comparison of research in relation to data collection is present. A comparison of research in relation to data collection is clearly provided and well developed. A comprehensive comparison research in relation to data collection is thoroughly developed with supporting details.

Required Sources 5.0% Sources are not included. Number of required sources is only partially met. Number of required sources is met, but sources are outdated or inappropriate. Number of required sources is met. Sources are current, but not all sources are appropriate for the assignment criteria and nursing content. Number of required resources is met. Sources are current, and appropriate for the assignment criteria and nursing content.

Presentation 10.0% The piece is not neat or organized, and it does not include all required elements. The work is not neat and includes minor flaws or omissions of required elements. The overall appearance is general, and major elements are missing. The overall appearance is generally neat, with a few minor flaws or missing elements. The work is well presented and includes all required elements. The overall appearance is neat and professional.

Mechanics of Writing (includes spelling, punctuation, grammar, and language use) 5.0% Surface errors are pervasive enough that they impede communication of meaning. Inappropriate word choice or sentence construction is employed. Frequent and repetitive mechanical errors distract the reader. Inconsistencies in language choice (register) or word choice are present. Sentence structure is correct but not varied. Some mechanical errors or typos are present, but they are not overly distracting to the reader. Correct and varied sentence structure and audience-appropriate language are employed. Prose is largely free of mechanical errors, although a few may be present. The writer uses a variety of effective sentence structures and figures of speech. The writer is clearly in command of standard, written, academic English.

Documentation of Sources (citations, footnotes, references, bibliography, etc., as appropriate to assignment and style) 5.0% Sources are not documented. Documentation of sources is inconsistent or incorrect, as appropriate to assignment and style, with numerous formatting errors. Sources are documented, as appropriate to assignment and style, although some